Reduce TNF-α by 62% with Omega-7 & DHA

Chronic inflammation is increasingly recognized as a central contributing factor to aging and age-related diseases—a phenomenon often referred to as "inflammaging." This persistent low-grade inflammatory state accelerates cellular senescence, impairs immune function, and increases the risk of developing metabolic disorders, cardiovascular diseases, and other chronic illnesses associated with aging. A key strategy to address inflammaging and its related complications is through targeted nutritional interventions that modulate inflammatory pathways.

Omegia™ Omega-7-rich sea buckthorn oil has demonstrated significant anti-inflammatory potential, primarily due to its high concentration of palmitoleic acid, a monounsaturated fatty acid (MUFA). Scientific studies show that Omega-7 fatty acids from sea buckthorn oil can effectively reduce key inflammatory markers such as TNF-α, IL-6, IL-1β, MIP-3α, and I-selection, thus acting through pathways distinct from those regulated by Omega-3 fatty acids like DHA. Clinical research has specifically highlighted Omegia™ Omega-7's ability to substantially reduce C-reactive protein (CRP)—a well-established marker of systemic inflammation—by up to 49%, as well as decrease TNF-α levels by approximately 26%, reinforcing its strong anti-inflammatory profile.

Recent studies further illustrate the complementary and synergistic effects of Omega-7-rich sea buckthorn oil when combined with Omega-3 DHA. Our latest research revealed that this combination significantly amplifies anti-inflammatory outcomes, achieving remarkable reductions in pro-inflammatory cytokines such as IL-6 by 48% and TNF-α by 62%. At the same time, the combination increased beneficial anti-inflammatory cytokine IL-10 by 60%.

These findings suggest that Omegia™ Omega-7-rich sea buckthorn oil not only serves as an effective standalone dietary solution for inflammation management but also significantly enhances the anti-inflammatory and cardioprotective effects of DHA-based formulations. Thus, incorporating Omega-7 into dietary supplements or functional foods represents a promising nutritional strategy to mitigate inflammaging, support cardiovascular health, and potentially slow down the aging process .

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Featured Ingredient

Omega 3 ≥ 13%
Omega 6 ≥ 10%
Omega 7 ≥ 30%
Omega 9 ≥ 18%
Beta-carotene ≥ 100 mg/100g
Vitamin E ≥ 450 mg/100g

Available in oil and cold-water-soluble powder
TRI-CAP™ Microencapsulated
Sustainably & Responsibly Made

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Reference

Bernstein A. et al. (2014), Journal of Clinical Lipidology, 8(6):612-617.

Chan E. et al. (2024), Journal of Functional Foods, 112:105973.

Li, J. et al. (2025) Food & Function,16:1241-1253